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Dutasteride uk hair loss has been linked not only with male pattern baldness, but also with other effects such as acne. The study suggests an important role for both androgens, estrogen and other compounds in the development of hair loss. findings may also have important implications for the treatment of male pattern baldness. "We found that hair follicles in the base of hair shaft contain higher concentrations of testosterone and estrogen than in other organs of the body. We also found that changes in these androgen and estrogen levels occur early in the disease process", explained Dr. Tülke H. "In order to better understand hair loss, we have to focus on the causes, including interaction between androgens and estrogen in men. For that reason, we can't dismiss the possibility that hair, and possibly other body organs, may be affected by the sex steroids." In order to examine further the possible link between hair follicles and other organs, the researchers collected hair samples from 50 healthy men between the ages of 35 and 68 years. By analyzing DNA, the scientists can tell man's past dutasteride prescription uk and present age, ethnicity whether he has a family history of polycystic ovary syndrome, a type of hormone-mediated ovarian cysts. They also examined the hair follicles for growth and found that more testosterone was detected in the more sensitive, basal follicles which usually contain low concentrations of the female sex hormones. higher testosterone levels were also detected in the areas of brain responsible for hair follicle development. In order to explain part the link between a hormone and hair loss, the researchers looked at role of hormones in the development hair follicles. According to Dr. Tülke H., women secrete androgens primarily in their ovaries and hair follicles. In men, androgens are created through a process called aromatization, which is the conversion of testosterone to oestrogen. find out what happens to androgen levels when androgens order dutasteride uk are produced from aromatized testosterone, the researchers analyzed their levels in the same testicular tissue samples that had been collected for hair growth. They found that at the very highest levels in testicles, testosterone and oestrogen levels were in the female pattern. basal follicles, where hair is most vulnerable during growth, generic avodart dutasteride however, testosterone was in the male pattern. Dr. Tülke H. explained that these results may explain why people with prostate cancer often develop baldness. "When androgens are released to the body, they trigger creation of a certain type stem cell, which in turn induces hair growth. It was found that the basal follicles express androgens, and that these androgen-dependent cells can then be differentiated into different cell types. Thus, it appears that the androgens normally are converted to oestrogen responsible for the initiation of hair follicle development, while those that are converted to testosterone in fact not required", he told SINC. Finally, when studying blood from the follicles of 50 healthy men while they were receiving the treatments with or without testosterone replacement therapy (TRT), the researchers discovered an association between lower testosterone in these people and facial hair or beard growth. If the levels of both testosterone and oestrogen were lowered to a certain threshold, positive response could be seen in facial hair that previously had seemed thin and fragile. "This research demonstrates that hair follicles have a crucial role in hair growth", Dr. Tülke H. explained. "Androgens are also important factors in this process, since they induce the release of androgens, a very important hormone that plays a key role in the induction and maintenance of hair follicle growth. Androgens are the most important male sex hormones, because without proper regulation, men develop conditions such as testicular cancer and baldness." ### Original press release published here: http://www.
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